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The FDA began regulating tobacco products in 2009 with the passage of the Family Smoking Prevention & Tobacco Control Act

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Acknowledgements The authors research is supported by US National Cancer Institute grants P01 CA-138338 (S.S.H.), R01 CA-081301 (S.S.H.) and P01 CA-217806 (D.K.H.) and by US National Institute on Drug Abuse grant U54 DA-031659 (D.K.H.)

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